MELD SCORE BETA

MELD Na SCORE

Stephen Z. Fadem, M.D

MELD = 3.78[Ln serum bilirubin (mg/dL)] + 11.2[Ln INR] + 9.57[Ln serum creatinine (mg/dL)] + 6.43

All lower boundaries are 1
MELDNa = MELD - Na - [0.025 X MELD X (140 - Na)] + 140

Sodium boundary is between 150-140
MELDRefit=4.082[Ln serum bilirubin (mg/dL)] + 10.671[Ln INR] + 8.485[Ln serum creatinine (mg/dL)] + 7.432

creatinine boundary is between .8 and 3.0. INR is between 1 and 3. Bilirubin_c is between 1 and 20.

MELDRefit_Na=4.258[Ln serum bilirubin(mg/dL)] + 6.792[Ln serum creatinine (mg/dL)] + 8.290[Ln INR] + 0.652 X (140-Na) − 0.194[(140-Na)] X serum bilirubin_c(mg/dL) + 6.327

Serum bilirubin in mg/dL
INR
Serum creatinine in mg/dL
Serum sodium in mmol/L

---

PREDICTOR	SCORE	MORTALITY
MELD	___	__
MELDNa	___	___
MELDRefit	___	___
MELDRefitNa	___	___

MELDNa: Meld score combined with serum sodium is an important predictor of mortality in patients on a liver transplant waiting list. N Engl J Med 2008;359:1018-26.
Gastroenterology. 2011 Jun;140(7):1952-60