CKD EPI & MDRD GFR Calculator - (With SI Units)

4 variable MDRD CKD EPI Equation (with SI Units) using standardized serum creatinine, age, race, gender

by Stephen Z. Fadem, M.D., FACP, FASN

Beta version - currently under review
Serum creatinine
mg/dL μmol/L

NOTE: CKD EPI GFR is only valid with creatinine methods are traceable to IDMS
Age years
Race African American All other races*
Gender Male Female
TRACEABLE TO IDMS No Yes
CKD EPI Value: epi


MDRD GFR: epi


(Age, Race, Gender, Plasma creatinine)

Chronic kidney disease (GFR less than 60 or kidney damage for at least three months)
*All ethnic groups other than African American


REFERENCES:


  • Andrew S. Levey, MD; Lesley A. Stevens, MD, MS; Christopher H. Schmid, PhD; Yaping (Lucy) Zhang, MS; Alejandro F. Castro III, MPH; Harold I. Feldman, MD, MSCE; John W. Kusek, PhD; Paul Eggers, PhD; Frederick Van Lente, PhD; Tom Greene, PhD; and Josef Coresh, MD, PhD, MHS, for the CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration). A New Equation to Estimate Glomerular Filtration Rate. Ann Intern Med. 2009 May 5;150(9):604-12

  • Expressing the Modification of Diet in Renal Disease Study Equation for Estimating Glomerular Filtration Rate with Standardized Serum Creatinine Values. Clin. Chem, 2007 Apr;53(4):766-72. Epub 2007 Mar 1.

  • A more accurate accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group Ann Intern Med 1999 Mar 16; 130 (6): 461-70.

  • A.S. Levey, T. Greene, J.W. Kusek, G.L. Beck, MDRD Study Group. A simplified equation to predict glomerular filtration rate from serum creatinine (abstract) J Am Soc Nephrol 2000 Sep; 11:155A

  • Levey AS, Coresh J, Greene T, Stevens LA, Zhang YL, Hendriksen S, Kusek JW, Van Lente F; Chronic Kidney Disease Epidemiology Collaboration. Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate. Ann Intern Med. 2006 Aug 15;145(4):247-54.

  • AACC - American Association of Clinical Chemistry Q & A with W. Gregory Miller, PhD, DABCC, FACB

  • G.L. Myers, W.G. Miller, J. Coresh, J. Fleming, N. Greenberg, T. Greene, T. Hostetter, A.S. Levey, M. Panteghini, M. Welch, and J.H. Eckfeldt. Recommendations for improving serum creatinine measurement: A report from the laboratory working group of the National Kidney Disease Education Program. Clinical Chemistry 2006 52: 5-18.

  • Stevens LA, Coresh J, Feldman HI, Greene T, Lash JP, Nelson RG, Rahman M, Deysher AE, Zhang YL, Schmid CH, Levey AS. Evaluation of the modification of diet in renal disease study equation in a large diverse population J Am Soc Nephrol. 2007 Sep; 18(10):2749-57

  • Madero M, Sarnak MJ, Stevens LA. Serum cystatin C as a marker of glomerular filtration rate Curr Opin Nephrol Hypertens. 2006 Nov;15(6):610-6


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