Solute Excretion

programmed by Stephen Z Fadem

V = Volume in liters
CH2O=Freewater clearance
Cosm=Osmolar clearance =( Uosm X V)/Posm
V=Freewater clearance + osmolar clearance
Freewater clearance=V - osmolar clearance
CH2O=V(1- (Uosm/Posm))
Solute excretion=V X Uosm
V=Solute excretion/Uosm Free water=Solute excretion/Uosm X (1- (Uosm/Posm)

Urine Volume (liters)
Urine omolality (mosms)
Plasma omolality (mosms)
The U/P osm is
The Cosm is
The free water clearance is
The solute excretion is mOsm/day
Change solute excretion: mOsm/day (beer potomania might be 300 mOsm/day)
Free water clearance now is liters per day.

© 2008-22, Stephen Z. Fadem, M.D., FASN. All rights reserved. No part of this application may be duplicated without written permission from the author.


The licensee or user understand and agree that the technology and content of this application are provided for educational purposes only. All calculations must be checked for accuracy and confirmed before use, clinical or otherwise. All medical decisions must be based upon the clinical judgment of a licensed physician. Licensee or user assumes the duty to have any and all laboratory values or calculations verified by a licensed physician. Neither licensor nor its associated authors or other entities warrant the accuracy of any information provided by or resulting from the technology or the content for clinical management, and licensee or user agree that no such persons or entities shall be liable for any adverse consequences resulting from the use of any of the same.

Licensee or user shall indemnify, defend and hold harmless licensor, its affiliates, and their respective officers, directors, owners, agents, information providers and employees from and against any claims, demands or causes of action whatsoever, including without limitation those arising on account of, or resulting from the exercise or practice of the license granted hereunder by licensee, its sublicensees, if any, its subsidiaries or other officers, employees, agents or representatives.